Best Natural Antihistamine: No More Allergies[Guide 2021]

Are you tired of having medical treatments for your allergies and their side effects?

This article is to tell you about the best Natural Antihistamines and the science behind them.

Histamine is a protein produced by the body during allergic reactions which cause rashes and itching, swelling, sneezing and breathing problems, and much more.

There are several over-the-counter (OTC) and prescriptions available that are effective and give instant relief to the symptoms but along with this they also cause side effects like diarrhea, nausea, and drowsiness. This is the reason some people prefer going for natural antihistamine foods as it is said natural things give out long-lasting results as compared to chemical-induced things.

Best Natural Antihistamines and science behind them


Butterbur is a plant whose leaves are generally used to wrap butter during warm weather but besides this, it has numerous medicinal purposes. It is highly grown in Europe and also in some mild parts of Asia.

Butterbur is also known for curing migraine and hay fever which are also popular as allergic rhinitis.

The extract of butterbur shrub can have some antihistamine properties as per the research.

Although, butterbur extract contains certain chemicals that might relieve spasms and help in decreasing swelling and inflammation. On the other hand, there are also some raw butterbur extracts available in the market that contain compounds called alkaloids which can cause liver damage and even cancer.

So one needs to be selective and alert while purchasing raw butterbur extract from the market.
People who have sensitivity issues to ragweed, daisies, chrysanthemums, and marigolds are advised to not consume butterbur.


Vitamin C has always been very advantageous whenever it comes to skin. It works for the skin like nothing but magic.

Being a powerful antioxidant and anti-inflammatory, it has proven itself when it comes to treating any type of allergies.

Vitamin c rich foods that works as a natural antihistamine
Vitamin c rich foods

The researchers have found that a little heavy dose (about 2 grams) of Vitamin-C is useful in treating the symptoms of all types of allergies.

Some of the vitamin-C rich fruits and vegetables easily available in the market are –

  • Pineapple
  • Kiwi
  • Strawberry
  • Broccoli
  • Kale
  • Bell peppers
  • Tomato
  • Papaya
  • Guava
  • Orange

Including these vitamin-C rich fruits and vegetables in our diet, not just helps our body to fight our histamine but also helps in boosting our immune system.

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Bromelain is an enzyme that is commonly known for helping in the digestion of protein in the body. It can be easily found in the core and juice of pineapples.

It is effective for the treatment of swelling of inflammation due to allergies and also in respiratory problems.

Bromelain can also be used in reducing allergic sensitization and allergic airway disease which was found while performing research on mice.

According to the study, it is suggested that consumption of 400-500 mg of bromelain three times a day daily can help in making the body fight against all the histamine problems.

In some of the cases, oral intake of bromelain has shown the side effects such as –

  • Increased heart rate
  • Menstrual discontinuation
  • Digestive problem

That is why it is advised for such people to avoid the consumption of pineapples in any form.


Quercetin is a natural flavonoid which is easily available in fruits, vegetables as well as grains.

It has certain anti-inflammatory properties which are found to be helpful in the reduction of symptoms of allergies.

Some of the quercetin rich edible items are –

  • Red onions
  • Apples
  • Red vine
  • Grapes
  • Citrus Fruits
  • Coffee
  • Green tea
  • Berries
  • Capers

Quercetin is also linked with treating several chronic diseases including cancer and other heart diseases, diabetes, and also degenerative brain disorders.

However, there are also supplements of quercetin easily available in the market. As per the study, consuming quercetin supplements works better in the treatment of allergies as compared to taking it directly from fruits and other edibles as they contain the flavonoids in less amount.

Before consuming quercetin as a supplement, a prescription from a nutrition expert is a must for some people taking a very high dose, especially in the long-run can result in kidney damage.


Our body is full of good and bad bacterias. Probiotics are said to be good bacteria which help in boosting up the immune system of the body and can fight against histamines to reduce the symptoms of allergies.

natural antihistamine foods that includes probiotics
List of Probiotics rich foods

Here are some of the probiotics rich food

  • Yogurt
  • Kefir
  • Sauerkraut
  • Pickles
  • Traditional Buttermilk
  • Cheddar, mozzarella, and gouda cheese
  • Natto

According to the NCCIH, all probiotics may not help cure the allergy, some may work and some may not.


Stinging nettle is a herb that is mainly found in parts of the United States of America, Europe, and Canada. It has nettles with sharp hairy leaves that contain certain chemicals like formic acid and histamine.

Besides the fact that it contains histamine, it is used as a natural histamine to treat allergies.

According to research, some participants were asked to take 300 mg of freeze-dried nettles regularly, where 58% got relieved from their allergies and 68% accepted it as better than the placebo.

Stinging nettle is also known for treating arthritis and reducing inflammation which further helps in the betterment of osteoarthritis pain (OA).

However, stinging nettle is also available in the form of supplements in the stores which is easy for oral consumption as compared to naturally taken.


NAC is an essential antioxidant that is already present inside the body, formed with the help of amino acids.

It is found in the food products that are high in protein. Some of them are-

  • Legumes
  • Turkey/chicken
  • Yogurt
  • Curd
  • Cheese
  • Sunflower seed
  • eggs

NAC is essential as it plays an important role in detoxifying the body.

Its antioxidant and anti-inflammatory nature is not just helpful in the treatment of allergic symptoms but also prevents and reduces kidney and liver damage.

NAC does not reduce histamine levels. It breaks up the mucous-like Esposito, which when overproduced by the body, brings the side effect of inviting the allergens.


Besides using the natural remedies directly in the form of food there is a broad range of supplements available in the market which is affordable and even proved to be working on allergies.


D-Hist consists of all the main components that are proven effective in the treatment of allergies. It is a combination of Vitamin-C, quercetin, stinging nettle, bromelain, and NAC which reduces the swelling.

Signs of side-effects like drowsiness and nausea are also exceptional which commonly accompanies most of the allergic treatments.


Hist- guard is also formulated with an adequate amount of basic and most essential components and one of the most rated natural anti-histamine.

It can be used for the treatment of itchiness, swollen eyes, runny or stuffy nose, hay fever, and many more symptoms of allergies.


This medicine consists of many natural ingredients along with stinging nettle leaf extract, quercetin, Vitamin-C, and bromelains like turmeric which itself is a natural antioxidant and helps in the reduction of pain, swelling, and inflammation.

It helps to promote maximum comfort to the skin, respiratory and digestive issues.

According to the users, it is better than chemical medicines like Allegra and Claritin and works well for sneezing, congestion, and relaxing itchy eyes.


This supplement is designed and formulated with natural wild berries extract, bromelain, and NAC that helps in the reduction of respiratory symptoms of allergy.

It is specially crafted to break down the mucus and promote oxygen flow in the body. People with asthma and sinus issues can also get relief from the consumption of this supplement.


This supplement is a powerful supplement as well as serves multi-purpose.

It can be taken while treating the allergies caused by animals like cats or rats, seasonal allergies like rashes, and hay fever.

The same supplement even works on the kids just by depleting the amount of dose. However, it can also be taken just to improve the immune system.


Nettle is one of the absolute and certified supplements which consists of only organic freeze and dried nettle tablets. It is even certified for being organic.

Best for those who prefer organic and gluten-free products. It works well for a runny nose and itchy eyes.

It has also shown good results in the treatment of hives and itchy skin. That’s why Nettle is considered a natural antihistamine for hives.


Mega Quercetin has shown good effects when it comes to the treatment of seasonal allergies like itching or rashes. Its formulation includes vitamin-C, bromelain, quercetin along with some natural ingredients like vegetable cellulose.

If a person is allergic to animals like cats or dogs then this natural antihistamine works well.

It is also effective for the treatment of sinus and respiratory issues.


Ready for pollen is a certified organic supplement. It contains all the natural ingredients like extracts of stinging nettle, astragalus root extracts, ginger rhizome extracts.

It comes in the form of a spray and is easy to apply in the infected area. Hence, it seems an easy and effective way to fight through pollens and allergens.


Aller -response is a combination of natural as well as some chemical ingredients.
It is formulated with turmeric extracts, bromelain, quercetin, amla fruit, pepper fruit extracts, and stinging nettle leaf.

All these ingredients give a natural touch to this supplement to fight against allergens and cure the infections.

It also acts as a great immune booster and is capable of reducing ear infection, fatigue, sneezing, watery eyes, and coughing to a great extent.


Respir boost is specially designed to comfort those, who are more prone to respiratory problems during seasonal allergies.

The butterbur extract and Vitamin c along with a few other important ingredients like pine bark and stinging nettle leaf extract and bromelain support your body to detox and promote healthy lungs with a regular flow of oxygen.

It is also helpful in curing a long time existing coughs, chronic bronchitis, and other chest infections.


The unique part about this supplement is that it can cure the allergies of both animals as well as humans.

Alfalfa which is a medicinal plant which is being used for many years to cure many diseases.

The maximum used ingredient of this product is Alfalfa only. This supplement has treated seasonal allergies, breathing issues, itching in the body as well as in the eyes successfully.


The White lung is a natural antihistamine supplement that is formulated with vitamin-C and bromelain as its main and most effective ingredients along with others.

It is a supporter of healthy lungs by detoxifying and cleansing them and reduces the symptoms of allergy. It helps in reducing long term asthmatic issues and also normalizes the blood pressure.


Allergy relief is meant to treat the symptoms of allergy such as itching in the body especially in the eyes, runny nose, throat congestion, and also hay fever.

The effect of a one-time use of this supplement gives relief for about 24 hours which makes its product to be used to get rid of allergic symptoms.


This tablet is used to cure symptoms like rashes, hives, and congestions especially along with normal allergic symptoms.

It is made by using a homeopathic approach so it has no side effects and is safe to use and get rid of allergens.


Complete allergy is an antihistamine syrup that is specially made for kids age between 2-12 years. This syrup gives them relief from all the symptoms of allergy-related to the eyes and nose and throat.

There is no side effect of this medicine like drowsiness or nausea since it is made by keeping a child’s health in mind.


Tecnu is easy to apply to the cream-based product. This is formulated with natural ingredients like extracts of poison oak, ivy, and sumac.

This cream is especially for those who are suffering from allergic symptoms like hives, rashes, or extreme itching.

This cream should be kept out of the reach of children since it is made up of poisonous natural tree leaves and should be taken only on the prescription of the doctor.


Aveeno is a lotion that is highly prescribed by the dermatologist for the allergic itches which are caused by insect bites or chickenpox treatment.

The most effective ingredient of this product is calamine and poison ivy which acts faster on the itches and gives soothing relief.


Clearlife is a nasal spray that is made by using homeopathic ingredients. It works well as an antihistamine to treat respiration as well as eyes and throat related seasonal allergic symptoms.

This spay provides natural relief without any feeling of dizziness, or dryness in the body.


Xlear max is a homeopathic nasal spray that helps to reduce the tissue swelling from pollen, pollution, bacteria, and all the other allergens and irritants.

It helps in curing severe sinus pressure caused due to nasal congestion. It is also useful in reducing snoring by cleaning the nasal passage.


Allegra is one of the fastest-acting antihistamines which gives instant relief from outdoor to indoor allergy symptoms for a longer period.

It starts attacking the allergens in a few minutes of consumption and helps in curing hives and rashes and also acts upon sneezing, runny nose, and watery eyes.

A high dose gives a side -effect like the feeling of dizziness. It is easily available over the counter but should be taken only on the prescription of the doctor.



Natural things always work better for our bodies. All the food products mentioned in this article are natural sources to increase your immunity and to fight back to histamine and allergy.

One should take care of a proper, healthy, and balanced diet which includes all the nutrients in adequate quantities. This can be the only best and natural antihistamine.

Besides, there are also natural supplements available to fulfill the requirement of people who do not have sufficient time to include all the items in their diet on a regular basis.


There are various ways to get instant relief from the allergy especially when it comes to symptoms like itching, redness, swelling or inflammation, or even fungal allergies.

One of them is has vitamin-c and skin remunerating property that gives instant relaxation and soothes the allergy when applied directly upon the infected area.

Another treatment is tea tree oil or calendula oil. They also perform well in healing the effects of allergy and give instant relief.


Yes, ginger is a natural antihistamine. It is useful in reducing the nasal symptoms of allergy. Its extracts can be used as an alternative treatment for patients with Allergic Rhinitis(AR).


Apple Cider Vinegar is also recommended by experts as a natural way to boost the immune system. It helps to break down the mucus and to promote lymphatic drainage.

Drinking 2 tablespoons of apple cider vinegar with a glass of water added with lemon juice thrice a day regularly helps to get relief from allergic symptoms.


Lemon is one of the citrus fruits. It consists of a good amount of Vitamin-C which automatically puts it into the category of natural antihistamines.


Bananas also come under the category of good and natural antihistamines which helps in the promotion of reduction of allergic symptoms.


As per some scientific reports, coffee has certain properties to release histamine from the mast cell so it might be anti-allergic.

Histamine gets released by mast cells into the infected tissues when they come in contact with substances such as pollens and dust.


Garlic is one of those superfoods which has the ability to help the immune system work normally by fighting against the free radical cell known as allergens until they are completely removed out of the body.


  • Fermented dairy products
  • fermented vegetables like sauerkraut and kimchi
  • Pickles
  • Fermented meats
  • Wine, beer, alcohol, and such fermented drinks

Above given food items are some of the examples of the products that are high on histamine and along with them, there are several vegetables like spinach, eggplant, tomatoes, and fishes that can also be added to make a rich and high-in histamine diet to fight through allergy.


To stop the effect of allergy or to prevent yourself from having it, one should keep a few things in mind. Such as –

  1. Do not forget to wear masks or cover your face while stepping out of the house.
  2. When returning home, remove and rinse off the clothes that you have worn outside to remove the pollen and dust particles from them.
  3. Keep your lawns, gardens clean and also plants that are potted inside the house need to be taken care of on a regular basis because they stir up allergens
  4. Try to be at home at the time of dry and windy days. The best time for an outing is after the rain.
  5. Keep your indoors as much as clean.


In today’s world, protecting our body from allergies all the time is a bit difficult because of the increasing pollution. However, we can take certain precautions to keep us safe from pollen and bacterias.

Never ignore your allergy symptoms and always consult the doctor if the symptoms are getting worse rather than trying to cure it by yourself.

Try to practice self-care techniques daily and instead of taking a chemical antihistamine, go for the natural antihistamine home remedies because the effect of natural things always lasts for a long time.

Lastly, keep yourself stuck to a healthy diet that is full of all essential nutrients.

Thank You for reading 🙂 , Please leave your comment about this article below.

A Medicine Doctor, Educator, Motivator, and Speaker! Dr. DK Pandey (Known as Doctor DK) is recognized as a leader writer in Health; Wellness and Health Products.

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